Roxy Lanes, located in the old New Look store along the high street, will offer a variety of activities such as ten pin bowling, American pool, and air hockey.
Other activities include duckpin bowling, a batting cage, karaoke, basketball, shuffleboard, darts and more than 50 arcade games.
The venue is family friendly with under 18s welcome when accompanied by an adult until 7pm Sunday to Friday and 5pm on Saturdays.
Commercial manager Joel Mitchell said: “Following on from the successful launch of Roxy Lanes in Bristol and Cardiff, we’re excited to be heading back down south to open our next Roxy Lanes site, Roxy Lanes Cheltenham.
“The venue will have something for all ages.
“We look forward to seeing you all there!”
Founded by Matthew Jones and Ben Jones, Roxy Leisure opened their first Roxy site in Leed’s back in 2013.
Their newest Roxy Lanes venue opened in Cardiff in April this year.
Cheltenham will be the 17th site for the Roxy Leisure group with other locations in Leicester, Cardiff, Birmingham, Edinburgh, Sheffield, Bristol, Nottingham, Manchester, and Liverpool.